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Health & Medicine Pharmaceuticals & Biotech Science

SEFUNDA, LLC announces the Launch of their Crowdfunding Campaign

Sefunda, a Swiss based company established in early 2019, is a small, dedicated team of professionals with background in IVD product development, molecular epidemiology, medical device development and material science combined with business strategy and experience with well more than 100 years.

OUR MISSION:

Increase the safety of patients, reduce individual healthcare costs, promote antibiotic stewardship. 

We are all about finding the solution to a problem – using technology as a tool and not a purpose. We are a dedicated lean team of experienced professionals combining Swiss precision with creativity and visionary drive. Listening to real market needs, we understand the economics driving the health care sector and the intricacies of producing high volume consumables at low and affordable cost.

THE KEY PROBLEM:

Recent research shows that 30% – 50% of patients in the US receive incorrect antimicrobial treatment This can in part be attributed to inefficient or incorrect diagnostic processes. Even for the most common infections, the delay between testing and effective treatment can take up to 10 days.

OUR SOLUTION:

We make patient-tailored treatment truly accessible and affordable for everybody – delivering immediate actionable results for treatment decision where time matters most. Our rapid, cost-effective and easy to use testing platform empowers health care professionals to diagnose and treat patients within one single visit, normally less than 30 minutes. By combining robust, proven and adaptable technology with smart multiplexing capabilities, we bring the precision of a molecular diagnostics lab to your office.

WHAT SETS US APART?

We focus on the solution, not the technology. By building on robust and proven technology, we avoid «reinventing the wheel» and save money and time. Together with our American partner Tensentric, Boulder Co., Sefunda is building a business ecosystem, that enables us to build a cost effective, low barrier molecular diagnostics solution. A small, powerful team is building a PCR based molecular diagnostics solution, that is going to bring laboratory quality molecular diagnostics to your local clinic. Trade Secret agreements will keep the development from competitors copying our solution much longer than any IP.

CLIA waiver as door opener for the US market:

Background: The Clinical Laboratory Improvement Amendments of 1988 (CLIA) enabled greater access to low-risk tests by allowing their use in facilities with a Certificate of Waiver in the U.S. Recently, the 2019 novel coronavirus (COVID-19) pandemic has shined a spotlight on CLIA-waived diagnostic testing. To meet this increased patient demand for diagnostic testing, the U.S. Department of Health and Human Services (HHS) authorized licensed pharmacists to order and administer FDA authorized COVID-19 tests.

Financial Overview:

Below is the financial overview assuming one product, roll-out in late 2023, a market share of 3%, sales within the US only. We will be adding a second product in early 2024. Estimated exit value in 2024 is around US$100mio. 

*: estimates based under current US market conditions and known regulatory US environment.   

Total Projected Cost:  

Total estimated costs before getting cash positive in 2024 are expected to be approximately: US$35,000,000 US Dollar. 

SEFUNDA, LLC is committed to obtaining and providing the monies necessary to institute and complete this project in a timely manner. 

SEFUNDA, LLC Equity Crowdfunding Campaign, 

https://www.equitynet.com/c/sefunda-llc

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Science Technology

Nobel Prize in Physics Recognizes Black Hole Discoveries

COLLEGE PARK, MD, October 6, 2020 — The Royal Swedish Academy of Sciences has awarded the 2020 Nobel Prize in Physics to Roger Penrose “for the discovery that black hole formation is a robust prediction of the general theory of relativity” and to Reinhard Genzel and Andrea Ghez “for the discovery of a supermassive compact object at the centre of our galaxy.” Ghez is the fourth woman to win a Nobel Prize in Physics.

“APS congratulates the 2020 Nobel Laureates for their outstanding contributions to astrophysics, and the understanding of our universe,” said APS CEO Kate Kirby. “I sincerely hope that this award will inspire the next generation of physicists, especially young women, whom we are committed to supporting at every level.”

“I’m pleased to see the Swedish academy recognize a fourth woman Nobel Laureate,” said APS President Phil Bucksbaum. “Andrea Ghez joins Donna Strickland, Maria Goeppert Mayer, and Marie Curie as the only women with that distinction.”

Nobel Prize 2020 winners photo

Niklas Elmehed (c) Nobel Media

Half of the prize goes to the University of Oxford’s Penrose, whose research published in Physical Review Letters during the 1960s is considered the most important contribution to the general theory of relativity since its conception by Albert Einstein more than a century ago. In 1971, APS and the American Institute of Physics honored Penrose with the Dannie Heineman Prize for Mathematical Physics.

The other half of the prize is jointly awarded to Genzel and Ghez, both APS Fellows, who have provided some of the strongest evidence to date that the compact object at the center of the Milky Way known as Sagittarius A* is very likely a supermassive black hole. Genzel gave an invited talk at the 2020 APS April Meeting where he described the culmination of nearly 30 years of observations of the star S2, revealing that it orbits Sagittarius A* just as Einstein predicted, in the shape of a rosette rather than an ellipse. Genzel is co-director of the Max Planck Institute for Extraterrestrial Physics and professor emeritus at the University of California, Berkeley.

Glennys Farrar, chair of the APS Division of Astrophysics, said: “I’m thrilled that the Nobel Committee has recognized the critical importance of the work of Genzel and Ghez, which established beyond a doubt the existence of a supermassive black hole at the center of the Milky Way, and the work of Penrose with Stephen Hawking, predicting the existence of black holes.”

“Their work has made pioneering use of adaptive optics on the Keck telescope, and it has led to the understanding that supermassive black holes inhabit the centers of many galaxies,” said Bucksbaum.

APS recognized Ghez, a professor of astrophysics at the University of California, Los Angeles, early in her career with the 1999 Maria Goeppert Mayer Award for outstanding achievement by a woman in physics. She presented an overview of decades of research on the Galactic Center at a plenary session at the 2019 April Meeting in Denver, CO.

“As often happens in science, a conceptual breakthrough relies on developing powerful new tools, which then lead to other discoveries,” said Farrar. “The precise measurements of the Genzel and Ghez teams have not only verified aspects of General Relativity that had never before been tested, but have also led to much more accurate knowledge of the location of the Solar System in the Galaxy which will be valuable in many other applications.”

“For science to advance requires unbounded leaps of imagination, but such leaps must be subject to rigorous observational examination,” said APS President-Elect Sylvester James Gates, Jr. “So we see two dichotomies, both Illustrated in this Nobel Prize, with Penrose’s work as an example of the first while the work of Genzel and Ghez illustrate the latter.”

This is the tenth consecutive year Physical Review Letters, the flagship journal of the American Physical Society, has been cited in the scientific background materials of the physics or chemistry prizes. A recent analysis revealed that, since 1995, 28.5% of Nobel-winning research in physics appeared in Physical Review Letters, outpacing other leading publications such as The Astrophysical Journal (11.2%), Science (5.6%), and Nature (4.7%).

Journals Nobel 2020 chart

“The Physical Review journals are among the most-read and highest-cited peer-reviewed publications in physics and related disciplines, broadly trusted and valued by researchers around the world for more than 127 years,” said APS Publisher Matthew Salter.

The Nobel Prize, first awarded in 1901, is widely regarded as the highest honor in science, economics, and literature. Due to the ongoing COVID-19 pandemic, the 2020 award ceremony at Stockholm City Hall will be streamed online in December. Laureates will receive medals and diplomas in their home countries. The Nobel Foundation has increased the prize amount to 10 million Swedish krona (about 1.1 million US dollars) for the first